GMP Recombinant Human Tissue Factor-武汉恩玑生命科技有限公司

产品展厅

GMP Recombinant Human Tissue Factor

品牌：EnkiLife

产地：中国

型号：支

货号：PCH90060

价格： ￥1800/10μg
发布日期： 2024-11-30
更新日期： 2025-05-22

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产品详请

产地	中国
保存条件
品牌	EnkiLife
货号	PCH90060
用途	细胞培养用细胞因子
组织来源
细胞形态
是否是肿瘤细胞
保质期
器官来源
免疫类型
品系
生长状态
物种来源
包装规格	支
是否进口	否

产品名称	GMP Recombinant Human Tissue Factor
蛋白名	Tissue Factor
纯度	Greater than 95% as determined by reducing SDS-PAGE
内毒素	≤10 EU/mg
蛋白构建	Recombinant Human Tissue Factor is produced by our Mammalian cell expression system and the target gene encoding Ser33-Glu251 is expressed.
Accession #	P13726
蛋白标签	Tag free
表达宿主	Mammalian cell
种属	Human
预测分子量	23.98 kDa
蛋白形态	Lyophilized
储存缓冲液	PBS,5% mannitol and 0.01% Tween 80, pH7.4
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
稳定性&储存	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 52 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
复溶	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

分子别名

Tissue Factor; TF; Coagulation Factor III; Thromboplastin; CD142; F3

Bioactivity

背景介绍

Full-length tissue factor (TF) is a transmembrane receptor and cofactor for factor (F)VII/FVIIa. In addition to full-length TF, an alternative spliced (as) form of TF can be generated that lacks the transmembrane domain and is released fromcells. In contrast to TF, asTF has low procoagulant activity because it lacks the transmembrane domain. Tissue factor is expressed by cells around blood vessels, such as adventitial fibroblasts, and body surfaces, such as epithelial cells, and plays a critical role in hemostasis. TF also contributes to various forms of thrombosis. Many cancers, particularly adenocarcinomas, express high levels of TF. A high level of tumor TF expression is associated with poor prognosis in many types of cancers, including breast, prostate, colorectal, and pancreatic cancer.