GMP Recombinant Human BMP-7-武汉恩玑生命科技有限公司

产品展厅

GMP Recombinant Human BMP-7

品牌：EnkiLife

产地：中国

型号：支

货号：PCH90002

价格： ￥1800/10μg
发布日期： 2024-11-30
更新日期： 2025-05-22

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产品详请

产地	中国
保存条件
品牌	EnkiLife
货号	PCH90002
用途	细胞培养用细胞因子
组织来源
细胞形态
是否是肿瘤细胞
保质期
器官来源
免疫类型
品系
生长状态
物种来源
包装规格	支
是否进口	否

产品名称	GMP Recombinant Human BMP-7
蛋白名	BMP-7
纯度	Greater than 95% as determined by reducing SDS-PAGE
内毒素	≤10 EU/mg
蛋白构建	Recombinant Human BMP-7 is produced by our Mammalian cell expression system and the target gene encoding Met316-His431 is expressed.
Accession #	P18075
蛋白标签	Tag free
表达宿主	Mammalian cell
种属	Human
预测分子量	13.1 kDa
蛋白形态	Lyophilized
储存缓冲液	PBS,pH 7.4
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
稳定性&储存	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 5 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
复溶	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

分子别名

Bone morphogenetic protein 7; BMP-7; Osteogenic protein 1 (OP-1); Eptotermin alfa; BMP7; OP1

Bioactivity

The ED50 for this effect is 0.02-0.04 μg/ml.

背景介绍

Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a state of leptin-resistance, thus a protein-like BMP7 which acts through a leptin-independent pathway could give new therapeutic directions.