GMP Recombinant Human IL-7-武汉恩玑生命科技有限公司

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GMP Recombinant Human IL-7

品牌：EnkiLife

产地：中国

型号：支

货号：PCH90031

价格： ￥1500/10μg
发布日期： 2024-11-30
更新日期： 2025-05-22

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产品详请

产地	中国
保存条件
品牌	EnkiLife
货号	PCH90031
用途	细胞培养用细胞因子
组织来源
细胞形态
是否是肿瘤细胞
保质期
器官来源
免疫类型
品系
生长状态
物种来源
包装规格	支
是否进口	否

产品名称	GMP Recombinant Human IL-7
蛋白名	IL-7
纯度	Greater than 95% as determined by reducing SDS-PAGE
内毒素	≤10 EU/mg
蛋白构建	Recombinant Human IL-7 is produced by our Mammalian cell expression system and the target gene encoding Asp26-His177 is expressed.
Accession #	P13232
蛋白标签	Tag free
表达宿主	Mammalian cell
种属	Human
预测分子量	17.3 kDa
蛋白形态	Lyophilized
储存缓冲液	PBS,5% mannitol and 0.01% Tween 80, pH7.4
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
稳定性&储存	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 27 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
复溶	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

分子别名

Interleukin-7; IL-7; IL7

Bioactivity

The ED50 for this effect is ≤30ng/ml.

背景介绍

Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.