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- 品牌:EnkiLife
- 产地:中国
- 型号:50uL
- 货号:AMM03867
- 价格: ¥1200/支
- 发布日期: 2024-12-03
- 更新日期: 2025-05-22
产地 | 中国 |
品牌 | EnkiLife |
保存条件 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
货号 | AMM03867 |
用途 | WB,IHC-P |
应用范围 | |
抗原来源 | |
保质期 | |
抗体名 | PI3 Kinase p85 alpha (1C8) Mouse Monoclonal Antibody |
是否单克隆 | 是 |
克隆性 | |
靶点 | PIK3R1 |
适应物种 | Human,Mouse,Rat |
形态 | Liquid |
宿主 | Mouse |
标记物 | Unconjugated |
包装规格 | 50uL |
亚型 | IgG1 |
标识物 | |
浓度 | % |
免疫原 | |
是否进口 | 否 |
产品概述
产品名称(Product Name) |
PI3 Kinase p85 alpha (1C8) Mouse Monoclonal Antibody |
描述(Description) |
Primary antibody |
宿主(Host) |
Mouse |
应用(Application) |
WB,IHC-P |
种属反应性(Reactivity) |
Human,Mouse,Rat |
产品性能
偶联物(Conjugation) |
Unconjugated |
修饰(Modification) |
Unmodified |
同种型(Isotype) |
IgG1 |
克隆(Clonality) |
Monoclonal Antibody |
形式(Form) |
Liquid |
存放说明(Storage) |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
储存溶液(Buffer) |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
纯化方式(Purification) |
Affinity Purified |
免疫原
基因名(Gene Name) |
PIK3R1 |
别名(Alternative Names) |
PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha |
基因ID(Gene ID) |
5295 |
蛋白ID(SwissProt ID) |
P27986 |
产品应用
稀释比(Dilution Ratio) |
WB: 1/500-1/1000 IHC: 1/50-1/100 |
蛋白分子量(Molecular Weight) |
Calculated MW: 84 kDa; Observed MW: 84 kDa |
研究背景
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
研究领域
Signal Transduction