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- 品牌：EnkiLife
- 产地：中国
- 型号：50uL
- 货号：AMM03520
- 价格： ￥1200/支
- 发布日期： 2024-12-03
- 更新日期： 2025-05-22
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 保存条件 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 货号 | AMM03520 |
| 用途 | WB,ICC/IF |
| 应用范围 | |
| 抗原来源 | |
| 保质期 | |
| 抗体名 | JNK1 (1A4) Mouse Monoclonal Antibody |
| 是否单克隆 | 是 |
| 克隆性 | |
| 靶点 | MAPK8 |
| 适应物种 | Human,Mouse,Rat |
| 形态 | Liquid |
| 宿主 | Mouse |
| 标记物 | Unconjugated |
| 包装规格 | 50uL |
| 亚型 | IgG2a |
| 标识物 | |
| 浓度 | % |
| 免疫原 | |
| 是否进口 | 否 |
产品概述
| 产品名称（Product Name） |
JNK1 (1A4) Mouse Monoclonal Antibody |
| 描述（Description） |
Primary antibody |
| 宿主（Host） |
Mouse |
| 应用（Application） |
WB,ICC/IF |
| 种属反应性（Reactivity） |
Human,Mouse,Rat |
产品性能
| 偶联物（Conjugation） |
Unconjugated |
| 修饰（Modification） |
Unmodified |
| 同种型（Isotype） |
IgG2a |
| 克隆（Clonality） |
Monoclonal Antibody |
| 形式（Form） |
Liquid |
| 存放说明（Storage） |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液（Buffer） |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| 纯化方式（Purification） |
Affinity Purified |
免疫原
| 基因名（Gene Name） |
MAPK8 |
| 别名（Alternative Names） |
AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated protein kinase 8; Mitogen-activated protein kinase 8; MK08_HUMAN; p54 gamma; PRKM 8; PRKM8; Protein kinase JNK1; Protein kinase; mitogen-activated; 8; SAPK 1; SAPK gamma; SAPK1; Stress activated protein kinase JNK1; Stress-activated protein kinase 1; Stress-activated protein kinase JNK1; Tyrosine protein kinase JAK1 . |
| 基因ID（Gene ID） |
5599 |
| 蛋白ID（SwissProt ID） |
P45983 |
产品应用
| 稀释比（Dilution Ratio） |
WB: 1/500-1/1000 IF: 1/50-1/200 |
| 蛋白分子量（Molecular Weight） |
Calculated MW: 48 kDa; Observed MW: 46,54 kDa |
研究背景
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
研究领域
Signal Transduction
