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- 品牌：EnkiLife
- 产地：中国
- 型号：50uL
- 货号：AMM03708
- 价格： ￥1200/支
- 发布日期： 2024-12-03
- 更新日期： 2025-05-22
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 保存条件 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 货号 | AMM03708 |
| 用途 | WB,IHC-P |
| 应用范围 | |
| 抗原来源 | |
| 保质期 | |
| 抗体名 | CD45 Mouse Monoclonal Antibody |
| 是否单克隆 | 是 |
| 克隆性 | |
| 靶点 | PTPRC |
| 适应物种 | Human,Mouse |
| 形态 | Liquid |
| 宿主 | Mouse |
| 标记物 | Unconjugated |
| 包装规格 | 50uL |
| 亚型 | IgG1 |
| 标识物 | |
| 浓度 | % |
| 免疫原 | |
| 是否进口 | 否 |
产品概述
| 产品名称（Product Name） |
CD45 Mouse Monoclonal Antibody |
| 描述（Description） |
Primary antibody |
| 宿主（Host） |
Mouse |
| 应用（Application） |
WB,IHC-P |
| 种属反应性（Reactivity） |
Human,Mouse |
产品性能
| 偶联物（Conjugation） |
Unconjugated |
| 修饰（Modification） |
Unmodified |
| 同种型（Isotype） |
IgG1 |
| 克隆（Clonality） |
Monoclonal Antibody |
| 形式（Form） |
Liquid |
| 存放说明（Storage） |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液（Buffer） |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| 纯化方式（Purification） |
Affinity Purified |
免疫原
| 基因名（Gene Name） |
PTPRC |
| 别名（Alternative Names） |
PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45 |
| 基因ID（Gene ID） |
5788 |
| 蛋白ID（SwissProt ID） |
P08575 |
产品应用
| 稀释比（Dilution Ratio） |
WB: 1/500-1/1000 IHC: 1/50-1/100 |
| 蛋白分子量（Molecular Weight） |
Calculated MW: 147 kDa; Observed MW: 180-240kDa |
研究背景
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
研究领域
Immunology
