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- 品牌:EnkiLife
- 产地:中国
- 型号:50uL
- 货号:AMM03519
- 价格: ¥1200/支
- 发布日期: 2024-12-03
- 更新日期: 2025-11-14
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 保存条件 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 货号 | AMM03519 |
| 用途 | WB,ICC/IF,IP,ChIP |
| 应用范围 | |
| 抗原来源 | |
| 保质期 | |
| 抗体名 | Ku70 (7B1) Mouse Monoclonal Antibody |
| 是否单克隆 | 是 |
| 克隆性 | |
| 靶点 | XRCC6 |
| 适应物种 | Human,Monkey |
| 形态 | Liquid |
| 宿主 | Mouse |
| 标记物 | Unconjugated |
| 包装规格 | 50uL |
| 亚型 | IgG1 |
| 标识物 | |
| 浓度 | % |
| 免疫原 | |
| 是否进口 | 否 |
产品概述
| 产品名称(Product Name) |
Ku70 (7B1) Mouse Monoclonal Antibody |
| 描述(Description) |
Primary antibody |
| 宿主(Host) |
Mouse |
| 应用(Application) |
WB,ICC/IF,IP,ChIP |
| 种属反应性(Reactivity) |
Human,Monkey |
产品性能
| 偶联物(Conjugation) |
Unconjugated |
| 修饰(Modification) |
Unmodified |
| 同种型(Isotype) |
IgG1 |
| 克隆(Clonality) |
Monoclonal Antibody |
| 形式(Form) |
Liquid |
| 存放说明(Storage) |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| 纯化方式(Purification) |
Affinity Purified |
免疫原
| 基因名(Gene Name) |
XRCC6 |
| 别名(Alternative Names) |
XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box- |
| 基因ID(Gene ID) |
2547 |
| 蛋白ID(SwissProt ID) |
P12956 |
产品应用
| 稀释比(Dilution Ratio) |
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 ChIP: 1/20 |
| 蛋白分子量(Molecular Weight) |
Calculated MW: 70 kDa; Observed MW: 67 kDa |
研究背景
It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.
研究领域
Epigenetics and Nuclear Signaling
