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- 品牌:EnkiLife
- 产地:中国
- 型号:50uL
- 货号:AMM03579
- 价格: ¥1200/支
- 发布日期: 2024-12-03
- 更新日期: 2025-11-14
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 保存条件 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 货号 | AMM03579 |
| 用途 | WB,IHC-F,IHC-P,ICC/IF,IP |
| 应用范围 | |
| 抗原来源 | |
| 保质期 | |
| 抗体名 | XRCC4 (7C10) Mouse Monoclonal Antibody |
| 是否单克隆 | 是 |
| 克隆性 | |
| 靶点 | XRCC4 |
| 适应物种 | Human,Mouse,Rat |
| 形态 | Liquid |
| 宿主 | Mouse |
| 标记物 | Unconjugated |
| 包装规格 | 50uL |
| 亚型 | IgG1 |
| 标识物 | |
| 浓度 | % |
| 免疫原 | |
| 是否进口 | 否 |
产品概述
| 产品名称(Product Name) |
XRCC4 (7C10) Mouse Monoclonal Antibody |
| 描述(Description) |
Primary antibody |
| 宿主(Host) |
Mouse |
| 应用(Application) |
WB,IHC-F,IHC-P,ICC/IF,IP |
| 种属反应性(Reactivity) |
Human,Mouse,Rat |
产品性能
| 偶联物(Conjugation) |
Unconjugated |
| 修饰(Modification) |
Unmodified |
| 同种型(Isotype) |
IgG1 |
| 克隆(Clonality) |
Monoclonal Antibody |
| 形式(Form) |
Liquid |
| 存放说明(Storage) |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| 纯化方式(Purification) |
Affinity Purified |
免疫原
| 基因名(Gene Name) |
XRCC4 |
| 别名(Alternative Names) |
X ray repair cross complementing protein 4; DNA repair protein XRCC4; DNA double strand break repair |
| 基因ID(Gene ID) |
7518 |
| 蛋白ID(SwissProt ID) |
Q13426 |
产品应用
| 稀释比(Dilution Ratio) |
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 |
| 蛋白分子量(Molecular Weight) |
Calculated MW: 38 kDa; Observed MW: 38-45 kDa |
研究背景
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
研究领域
Epigenetics and Nuclear Signaling
