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产品展厅
XRCC4 (7C10) Mouse Monoclonal Antibody
  • 品牌:EnkiLife
  • 产地:中国
  • 型号:50uL
  • 货号:AMM03579
  • 价格: ¥1200/支
  • 发布日期: 2024-12-03
  • 更新日期: 2025-05-29
产品详请
产地 中国
品牌 EnkiLife
保存条件 Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
货号 AMM03579
用途 WB,IHC-F,IHC-P,ICC/IF,IP
应用范围
抗原来源
保质期
抗体名 XRCC4 (7C10) Mouse Monoclonal Antibody
是否单克隆
克隆性
靶点 XRCC4
适应物种 Human,Mouse,Rat
形态 Liquid
宿主 Mouse
标记物 Unconjugated
包装规格 50uL
亚型 IgG1
标识物
浓度 %
免疫原
是否进口

产品概述

产品名称(Product Name)

XRCC4 (7C10) Mouse Monoclonal Antibody

描述(Description)

Primary antibody

宿主(Host)

Mouse

应用(Application)

WB,IHC-F,IHC-P,ICC/IF,IP

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG1

克隆(Clonality)

Monoclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Purified

 

免疫原

基因名(Gene Name)

XRCC4

别名(Alternative Names)

X ray repair cross complementing protein 4; DNA repair protein XRCC4; DNA double strand break repair

基因ID(Gene ID)

7518

蛋白ID(SwissProt ID)

Q13426

 

产品应用

稀释比(Dilution Ratio)

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

蛋白分子量(Molecular Weight)

Calculated MW: 38 kDa; Observed MW: 38-45 kDa

 

研究背景

Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

 

研究领域

Epigenetics and Nuclear Signaling