Bak Rabbit Polyclonal Antibody-武汉恩玑生命科技有限公司

产品展厅

Bak Rabbit Polyclonal Antibody

品牌：EnkiLife

产地：中国

型号：50uL

货号：APRab03721

价格： ￥1200/支
发布日期： 2024-12-03
更新日期： 2025-05-22

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产品详请

产地	中国
品牌	EnkiLife
保存条件	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
货号	APRab03721
用途	WB,IHC-P,ICC/IF,FC,IP
应用范围
抗原来源
保质期
抗体名	Bak Rabbit Polyclonal Antibody
是否单克隆	否
克隆性	Polyclonal Antibody
靶点	BAK1
适应物种	Human,Mouse
形态	Liquid
宿主	Rabbit
标记物	Unconjugated
包装规格	50uL
亚型	IgG
标识物
浓度	%
免疫原
是否进口	否

产品概述

产品名称(Product Name)	Bak Rabbit Polyclonal Antibody
描述(Description)	Primary antibody
宿主(Host)	Rabbit
应用(Application)	WB,IHC-P,ICC/IF,FC,IP
种属反应性(Reactivity)	Human,Mouse

产品性能

偶联物(Conjugation)	Unconjugated
修饰(Modification)	Unmodified
同种型(Isotype)	IgG
克隆(Clonality)	Polyclonal Antibody
形式(Form)	Liquid
存放说明(Storage)	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液(Buffer)	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
纯化方式(Purification)	Affinity Chromatography

免疫原

基因名(Gene Name)	BAK1
别名(Alternative Names)	BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7
基因ID(Gene ID)	578
蛋白ID(SwissProt ID)	Q16611

产品应用

稀释比(Dilution Ratio)	WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
蛋白分子量(Molecular Weight)	Calculated MW: 23 kDa; Observed MW: 23 kDa

研究背景

Bak is a proapoptotic member of the Bcl-2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death.

研究领域

Cell Biology