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产品展厅
Cleaved-Caspase 4/5 p20 Rabbit Polyclonal Antibody
  • 品牌:EnkiLife
  • 产地:中国
  • 型号:50uL
  • 货号:APRab00843
  • 价格: ¥1200/支
  • 发布日期: 2024-12-03
  • 更新日期: 2025-05-22
产品详请
产地 中国
品牌 EnkiLife
保存条件 Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
货号 APRab00843
用途 WB,ELISA
应用范围
抗原来源
保质期
抗体名 Cleaved-Caspase 4/5 p20 Rabbit Polyclonal Antibody
是否单克隆
克隆性 Polyclonal Antibody
靶点 CASP4
适应物种 Human
形态 Liquid
宿主 Rabbit
标记物 Unconjugated
包装规格 50uL
亚型 IgG
标识物
浓度 %
免疫原
是否进口

产品概述

产品名称(Product Name)

Cleaved-Caspase 4/5 p20 Rabbit Polyclonal Antibody

描述(Description)

Primary antibody

宿主(Host)

Rabbit

应用(Application)

WB,ELISA

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Cleaved

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Chromatography

 

免疫原

基因名(Gene Name)

CASP4

别名(Alternative Names)

TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II

基因ID(Gene ID)

837/838

蛋白ID(SwissProt ID)

P49662/P51878

 

产品应用

稀释比(Dilution Ratio)

WB: 1/500-1/1000 ELISA: 1/10000

蛋白分子量(Molecular Weight)

Calculated MW: 43 kDa; Observed MW: 47,22 kDa

 

研究背景

CASP4 (caspase 4) encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, caspase 4 induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

 

研究领域

Cell Biology