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- 品牌：EnkiLife
- 产地：中国
- 型号：50uL
- 货号：APRab00843
- 价格： ￥1200/支
- 发布日期： 2024-12-03
- 更新日期： 2025-11-14
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 保存条件 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 货号 | APRab00843 |
| 用途 | WB,ELISA |
| 应用范围 | |
| 抗原来源 | |
| 保质期 | |
| 抗体名 | Cleaved-Caspase 4/5 p20 Rabbit Polyclonal Antibody |
| 是否单克隆 | 否 |
| 克隆性 | Polyclonal Antibody |
| 靶点 | CASP4 |
| 适应物种 | Human |
| 形态 | Liquid |
| 宿主 | Rabbit |
| 标记物 | Unconjugated |
| 包装规格 | 50uL |
| 亚型 | IgG |
| 标识物 | |
| 浓度 | % |
| 免疫原 | |
| 是否进口 | 否 |
产品概述
产品性能
免疫原
产品应用
研究背景
CASP4 (caspase 4) encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, caspase 4 induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
研究领域
Cell Biology
