PP2A alpha Rabbit Polyclonal Antibody-武汉恩玑生命科技有限公司

产品展厅

PP2A alpha Rabbit Polyclonal Antibody

品牌：EnkiLife

产地：中国

型号：50uL

货号：APRab00510

价格： ￥1200/支
发布日期： 2024-12-03
更新日期： 2025-05-22

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产品详请

产地	中国
品牌	EnkiLife
保存条件	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
货号	APRab00510
用途	WB,IHC-F,IHC-P,ICC/IF,ELISA
应用范围
抗原来源
保质期
抗体名	PP2A alpha Rabbit Polyclonal Antibody
是否单克隆	否
克隆性	Polyclonal Antibody
靶点	PPP2CA
适应物种	Human,Mouse,Rat
形态	Liquid
宿主	Rabbit
标记物	Unconjugated
包装规格	50uL
亚型	IgG
标识物
浓度	%
免疫原
是否进口	否

产品概述

产品名称(Product Name)	PP2A alpha Rabbit Polyclonal Antibody
描述(Description)	Primary antibody
宿主(Host)	Rabbit
应用(Application)	WB,IHC-F,IHC-P,ICC/IF,ELISA
种属反应性(Reactivity)	Human,Mouse,Rat

产品性能

偶联物(Conjugation)	Unconjugated
修饰(Modification)	Unmodified
同种型(Isotype)	IgG
克隆(Clonality)	Polyclonal Antibody
形式(Form)	Liquid
存放说明(Storage)	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液(Buffer)	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
纯化方式(Purification)	Affinity Purified

免疫原

基因名(Gene Name)	PPP2CA
别名(Alternative Names)	PPP2CA; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C
基因ID(Gene ID)	5515
蛋白ID(SwissProt ID)	P67775

产品应用

稀释比(Dilution Ratio)	WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
蛋白分子量(Molecular Weight)	Calculated MW: 36 kDa; Observed MW: 36 kDa

研究背景

PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

研究领域

Cell Biology