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产品展厅
ADAM10 Rabbit Polyclonal Antibody
  • 品牌:EnkiLife
  • 产地:中国
  • 型号:50uL
  • 货号:APRab00350
  • 价格: ¥1200/支
  • 发布日期: 2024-12-03
  • 更新日期: 2025-05-22
产品详请
产地 中国
品牌 EnkiLife
保存条件 Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
货号 APRab00350
用途 WB,IP
应用范围
抗原来源
保质期
抗体名 ADAM10 Rabbit Polyclonal Antibody
是否单克隆
克隆性 Polyclonal Antibody
靶点 ADAM10
适应物种 Human
形态 Liquid
宿主 Rabbit
标记物 Unconjugated
包装规格 50uL
亚型 IgG
标识物
浓度 %
免疫原
是否进口

产品概述

产品名称(Product Name)

ADAM10 Rabbit Polyclonal Antibody

描述(Description)

Primary antibody

宿主(Host)

Rabbit

应用(Application)

WB,IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

纯化方式(Purification)

Affinity Purified

 

免疫原

基因名(Gene Name)

ADAM10

别名(Alternative Names)

CDw156; CD156c; ADAM10; KUZ; MADM

基因ID(Gene ID)

102

蛋白ID(SwissProt ID)

O14672

 

产品应用

稀释比(Dilution Ratio)

WB: 1/500-1/1000 IP: 1/20

蛋白分子量(Molecular Weight)

Calculated MW: 84 kDa; Observed MW: 90,68 kDa

 

研究背景

The ADAM10 prodomain acts as a chaperone that stabilizes mature ADAM protein folding, and prevents target-protein shedding through inhibition of ADAM10 proteinase activity. Mature ADAM10 is the major α-secretase responsible for cleavage of Notch, APP, cadherins, and prion protein. The ADAM10 protein cleaves receptor tyrosine kinases and their associated ligands and displays a wide range of regulatory functions across related signaling pathways.

 

研究领域

Cell Biology