Caspase 11 Rabbit Monoclonal Antibody-武汉恩玑生命科技有限公司

产品展厅

Caspase 11 Rabbit Monoclonal Antibody

品牌：EnkiLife

产地：中国

型号：50uL

货号：AMRe01761

价格： ￥1350/支
发布日期： 2024-12-03
更新日期： 2025-05-22

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产品详请

产地	中国
品牌	EnkiLife
保存条件	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
货号	AMRe01761
用途	WB,IP
应用范围
抗原来源
保质期
抗体名	Caspase 11 Rabbit Monoclonal Antibody
是否单克隆	是
克隆性	Monoclonal Antibody
靶点	Casp4
适应物种	Human,Mouse,Rat
形态	Liquid
宿主	Rabbit
标记物	Unconjugated
包装规格	50uL
亚型	IgG
标识物
浓度	%
免疫原
是否进口	否

产品概述

产品名称(Product Name)	Caspase 11 Rabbit Monoclonal Antibody
描述(Description)	Recombinant Rabbit Monoclonal antibody
宿主(Host)	Rabbit
应用(Application)	WB,IP
种属反应性(Reactivity)	Human,Mouse,Rat

产品性能

偶联物(Conjugation)	Unconjugated
修饰(Modification)	Unmodified
同种型(Isotype)	IgG
克隆(Clonality)	Monoclonal Antibody
形式(Form)	Liquid
存放说明(Storage)	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液(Buffer)	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
纯化方式(Purification)	Affinity Purified

免疫原

基因名(Gene Name)	Casp4
别名(Alternative Names)	Caspl; ich-3; CASP-4; Casp11; CASP-11
基因ID(Gene ID)	12363
蛋白ID(SwissProt ID)	P70343

产品应用

稀释比(Dilution Ratio)	WB: 1/500-1/1000 IP: 1/20
蛋白分子量(Molecular Weight)	Calculated MW: 43 kDa; Observed MW: 43,38,25 kDa

研究背景

Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non-canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators.

研究领域

Cell Biology