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- 品牌：EnkiLife
- 产地：中国
- 型号：50uL
- 货号：AMRe01939
- 价格： ￥1350/支
- 发布日期： 2024-12-03
- 更新日期： 2025-05-22
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 保存条件 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 货号 | AMRe01939 |
| 用途 | WB,IHC-F,IHC-P,ICC/IF,IP |
| 应用范围 | |
| 抗原来源 | |
| 保质期 | |
| 抗体名 | Phospho-eIF4E (Ser209) Rabbit Monoclonal Antibody |
| 是否单克隆 | 是 |
| 克隆性 | |
| 靶点 | EIF4E |
| 适应物种 | Human,Mouse,Rat |
| 形态 | Liquid |
| 宿主 | Rabbit |
| 标记物 | Unconjugated |
| 包装规格 | 50uL |
| 亚型 | IgG |
| 标识物 | |
| 浓度 | % |
| 免疫原 | |
| 是否进口 | 否 |
产品概述
| 产品名称(Product Name) | Phospho-eIF4E (Ser209) Rabbit Monoclonal Antibody |
| 描述(Description) | Recombinant Rabbit Monoclonal antibody |
| 宿主(Host) | Rabbit |
| 应用(Application) | WB,IHC-F,IHC-P,ICC/IF,IP |
| 种属反应性(Reactivity) | Human,Mouse,Rat |
产品性能
| 偶联物(Conjugation) | Unconjugated |
| 修饰(Modification) | Phosphorylated |
| 同种型(Isotype) | IgG |
| 克隆(Clonality) | Monoclonal Antibody |
| 形式(Form) | Liquid |
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| 储存溶液(Buffer) | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| 纯化方式(Purification) | Affinity Purified |
免疫原
| 基因名(Gene Name) | EIF4E |
| 别名(Alternative Names) | EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein |
| 基因ID(Gene ID) | 1977 |
| 蛋白ID(SwissProt ID) | P06730 |
产品应用
| 稀释比(Dilution Ratio) | WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 |
| 蛋白分子量(Molecular Weight) | Calculated MW: 25 kDa; Observed MW: 25 kDa |
研究背景
eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
研究领域
Epigenetics and Nuclear Signaling
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