HIF1 beta Rabbit Monoclonal Antibody-武汉恩玑生命科技有限公司

产品展厅

HIF1 beta Rabbit Monoclonal Antibody

品牌：EnkiLife

产地：中国

型号：50uL

货号：AMRe03025

价格： ￥1350/支
发布日期： 2024-12-03
更新日期： 2025-05-22

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产品详请

产地	中国
品牌	EnkiLife
保存条件	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
货号	AMRe03025
用途	WB,IHC-P
应用范围
抗原来源
保质期
抗体名	HIF1 beta Rabbit Monoclonal Antibody
是否单克隆	是
克隆性	Monoclonal Antibody
靶点	ARNT
适应物种	Human,Mouse,Rat,Hamster
形态	Liquid
宿主	Rabbit
标记物	Unconjugated
包装规格	50uL
亚型	IgG
标识物
浓度	%
免疫原
是否进口	否

产品概述

产品名称(Product Name)	HIF1 beta Rabbit Monoclonal Antibody
描述(Description)	Recombinant Rabbit Monoclonal antibody
宿主(Host)	Rabbit
应用(Application)	WB,IHC-P
种属反应性(Reactivity)	Human,Mouse,Rat,Hamster

产品性能

偶联物(Conjugation)	Unconjugated
修饰(Modification)	Unmodified
同种型(Isotype)	IgG
克隆(Clonality)	Monoclonal Antibody
形式(Form)	Liquid
存放说明(Storage)	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液(Buffer)	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
纯化方式(Purification)	Affinity Purified

免疫原

基因名(Gene Name)	ARNT
别名(Alternative Names)	ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta
基因ID(Gene ID)	405
蛋白ID(SwissProt ID)	P27540

产品应用

稀释比(Dilution Ratio)	WB: 1/500-1/1000 IHC: 1/50-1/100
蛋白分子量(Molecular Weight)	Calculated MW: 87 kDa; Observed MW: 87 kDa

研究背景

HIF-1β is also known as AhR nuclear translocator (ARNT) due to its ability to partner with the aryl hydrocarbon receptor (AhR) to form a heterodimeric transcription factor complex. Together with AhR, HIF-1β plays an important role in xenobiotics metabolism. In addition, a chromosomal translocation leading to a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia. Studies also found that ARNT/HIF-1β expression levels decrease significantly in pancreatic islets from patients with type 2 diabetes, suggesting that HIF-1β plays an important role in pancreatic β-cell function.

研究领域

Cardiovascular