PHD1 Rabbit Monoclonal Antibody-武汉恩玑生命科技有限公司

产品展厅

PHD1 Rabbit Monoclonal Antibody

品牌：EnkiLife

产地：中国

型号：50uL

货号：AMRe03270

价格： ￥1350/支
发布日期： 2024-12-03
更新日期： 2025-11-14

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产品详请

产地	中国
品牌	EnkiLife
保存条件	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
货号	AMRe03270
用途	WB
应用范围
抗原来源
保质期
抗体名	PHD1 Rabbit Monoclonal Antibody
是否单克隆	是
克隆性	Monoclonal Antibody
靶点	EGLN2
适应物种	Human,Rat
形态	Liquid
宿主	Rabbit
标记物	Unconjugated
包装规格	50uL
亚型	IgG
标识物
浓度	%
免疫原
是否进口	否

产品概述

产品名称(Product Name)	PHD1 Rabbit Monoclonal Antibody
描述(Description)	Recombinant Rabbit Monoclonal antibody
宿主(Host)	Rabbit
应用(Application)	WB
种属反应性(Reactivity)	Human,Rat

产品性能

偶联物(Conjugation)	Unconjugated
修饰(Modification)	Unmodified
同种型(Isotype)	IgG
克隆(Clonality)	Monoclonal Antibody
形式(Form)	Liquid
存放说明(Storage)	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液(Buffer)	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
纯化方式(Purification)	Affinity Purified

免疫原

基因名(Gene Name)	EGLN2
别名(Alternative Names)	Estrogen-induced tag 6; HPH-3; PHD1
基因ID(Gene ID)	112398
蛋白ID(SwissProt ID)	Q96KS0

产品应用

稀释比(Dilution Ratio)	WB: 1/500-1/1000
蛋白分子量(Molecular Weight)	Calculated MW: 44 kDa; Observed MW: 44 kDa

研究背景

Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

研究领域

Cardiovascular