Ku70 Rabbit Monoclonal Antibody-武汉恩玑生命科技有限公司

产品展厅

Ku70 Rabbit Monoclonal Antibody

品牌：EnkiLife

产地：中国

型号：50uL

货号：AMRe03061

价格： ￥1350/支
发布日期： 2024-12-03
更新日期： 2025-05-22

发送咨询信息

产品详请

产地	中国
品牌	EnkiLife
保存条件	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
货号	AMRe03061
用途	WB,IHC-F,IHC-P,ICC/IF
应用范围
抗原来源
保质期
抗体名	Ku70 Rabbit Monoclonal Antibody
是否单克隆	是
克隆性	Monoclonal Antibody
靶点	XRCC6
适应物种	Human
形态	Liquid
宿主	Rabbit
标记物	Unconjugated
包装规格	50uL
亚型	IgG
标识物
浓度	%
免疫原
是否进口	否

产品概述

产品名称(Product Name)	Ku70 Rabbit Monoclonal Antibody
描述(Description)	Recombinant Rabbit Monoclonal antibody
宿主(Host)	Rabbit
应用(Application)	WB,IHC-F,IHC-P,ICC/IF
种属反应性(Reactivity)	Human

产品性能

偶联物(Conjugation)	Unconjugated
修饰(Modification)	Unmodified
同种型(Isotype)	IgG
克隆(Clonality)	Monoclonal Antibody
形式(Form)	Liquid
存放说明(Storage)	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液(Buffer)	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
纯化方式(Purification)	Affinity Purified

免疫原

基因名(Gene Name)	XRCC6
别名(Alternative Names)	XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-
基因ID(Gene ID)	2547
蛋白ID(SwissProt ID)	P12956

产品应用

稀释比(Dilution Ratio)	WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
蛋白分子量(Molecular Weight)	Calculated MW: 70 kDa; Observed MW: 70 kDa

研究背景

It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.

研究领域

Epigenetics and Nuclear Signaling