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- 品牌：EnkiLife
- 产地：中国
- 型号：50μg
- 货号：PEH1100
- 纯度：95
- 价格： ￥320/支
- 发布日期： 2025-06-23
- 更新日期： 2025-06-23
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 货号 | PEH1100 |
| 用途 | |
| 包装规格 | 50μg |
| 纯度 | 95% |
| CAS编号 | |
| 是否进口 | 否 |
| 产品名称 | Recombinant Human IGF-I |
| 英文名称 | IGF-I |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 | <0.5 EU/μg as determined by LAL test. |
| 蛋白构建 | Recombinant Human Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Gly49-Ala118 is expressed. |
| Accession | P05019 |
| 表达宿主 | E.coli |
| 种属 | Human |
| 预测分子量 | 7.6 KDa |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5 |
| 运输方式 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 50mM Acetic Acid.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1 |
| 背景介绍 |
| Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contains the N- and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids has 94% identity with mouse IGF-I and exhibits cross-species activity. IGF-1 binds IGF-IR, IGF-IIR, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF-1 expression is regulated by growth hormone. R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg (R) for the Glu(E) at position three, hence R3, and a 13 amino acid extension peptide at the N terminus. R3 IGF-1 has been produced with the purpose of increasing biological activity. R3 IGF-1 is significantly more potent than human IGF-I in vitro. |
注意事项
本司产品仅用于科研,不用于临床诊断