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- 品牌:EnkiLife
- 产地:中国
- 型号:50μg
- 货号:PEM0841
- 纯度:95
- 价格: ¥360/支
- 发布日期: 2025-06-23
- 更新日期: 2025-06-23
产地 | 中国 |
品牌 | EnkiLife |
货号 | PEM0841 |
用途 | |
包装规格 | 50μg |
纯度 | 95% |
CAS编号 | |
是否进口 | 否 |
产品名称 | Recombinant Mouse LR3-IGF-1 (C-6His) |
英文名称 | LR3 IGF-I/Long R3 IGF-1 |
纯度 | Greater than 95% as determined by reducing SDS-PAGE |
内毒素 | <1 EU/μg as determined by LAL test. |
蛋白构建 | Recombinant Mouse Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Gly49-Ala118 is expressed with a 6His tag at the C-terminus. |
Accession | P05017 |
表达宿主 | E.coli |
种属 | Mouse |
预测分子量 | 10.2 KDa |
制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM NaAc, pH 4.5. |
运输方式 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
稳定性&储存 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
分子别名 |
IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I;Somatomedin C; somatomedin-C |
背景介绍 |
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors. |
注意事项
本司产品仅用于科研,不用于临床诊断