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产品展厅
Recombinant Mouse LR3-IGF-1 (C-6His)
  • 品牌:EnkiLife
  • 产地:中国
  • 型号:50μg
  • 货号:PEM0841
  • 纯度:95
  • 价格: ¥360/支
  • 发布日期: 2025-06-23
  • 更新日期: 2025-06-23
产品详请
产地 中国
品牌 EnkiLife
货号 PEM0841
用途
包装规格 50μg
纯度 95%
CAS编号
是否进口
产品名称

Recombinant Mouse LR3-IGF-1 (C-6His)

英文名称

LR3 IGF-I/Long R3 IGF-1

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素

<1 EU/μg as determined by LAL test.

蛋白构建

Recombinant Mouse Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Gly49-Ala118 is expressed with a 6His tag at the C-terminus.

Accession

P05017

表达宿主

E.coli

种属

Mouse

预测分子量

10.2 KDa

制剂

Lyophilized from a 0.2 μm filtered solution of 20mM NaAc, pH 4.5.

运输方式

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

稳定性&储存

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

复溶

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.


分子别名
IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I;Somatomedin C; somatomedin-C


背景介绍
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor. IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.


注意事项

本司产品仅用于科研,不用于临床诊断