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- 品牌：EnkiLife
- 产地：中国
- 型号：50μg
- 货号：PEH1241
- 纯度：95
- 价格： ￥1780/支
- 发布日期： 2025-06-23
- 更新日期： 2025-06-23
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 货号 | PEH1241 |
| 用途 | |
| 包装规格 | 50μg |
| 纯度 | 95% |
| CAS编号 | |
| 是否进口 | 否 |
| 产品名称 | Recombinant Human NRG1Beta (245AA) |
| 英文名称 | NRG1-beta 1/HRG1-beta 1 ECD/NRG1/Pro-neuregulin-1/NRG1?beta 1 ECD Protein/Neuregulin1 beta 1/Neuregulin-1 beta 1/heregulin-beta1 |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 | <0.01 EU/μg as determined by LAL test. |
| 蛋白构建 | Recombinant Human Neuregulin-1 Beta is produced by our E.coli expression system and the target gene encoding Ser2-Lys246 is expressed. |
| Accession | AAA58639.1 |
| 表达宿主 | E.coli |
| 种属 | Human |
| 预测分子量 | 26.9 KDa |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Pro-neuregulin-1; Neuregulin-1 beta 1; NRG1-beta 1; HRG1-beta 1; EGF; NRG1; GGF; HGL; HRGA; NDF; SMDF |
| 背景介绍 |
| Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. The protein concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development. |
注意事项
本司产品仅用于科研,不用于临床诊断