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- 品牌:EnkiLife
- 产地:中国
- 型号:50μg
- 货号:PEH1377
- 纯度:95
- 价格: ¥760/支
- 发布日期: 2025-06-23
- 更新日期: 2025-06-23
产地 | 中国 |
品牌 | EnkiLife |
货号 | PEH1377 |
用途 | |
包装规格 | 50μg |
纯度 | 95% |
CAS编号 | |
是否进口 | 否 |
产品名称 | Recombinant Human NRG1Beta (71AA) |
英文名称 | NRG1-beta 1/HRG1-beta 1 EGF Domain/Neuregulin 1/NRG1?beta 1 EGF Domain/Neuregulin1 beta 1/Neuregulin-1 beta 1 |
纯度 | Greater than 95% as determined by reducing SDS-PAGE |
内毒素 | <1 EU/μg as determined by LAL test. |
蛋白构建 | Recombinant Human Neuregulin-1 Beta is produced by our E.coli expression system and the target gene encoding Thr176-Lys246 is expressed. |
Accession | Q02297-6 |
表达宿主 | E.coli |
种属 | Human |
预测分子量 | 8.2 KDa |
制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
运输方式 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
稳定性&储存 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
分子别名 |
Pro-neuregulin-1; Neuregulin-1 beta 1; NRG1-beta 1; HRG1-beta 1; EGF;NRG1; GGF; HGL; HRGA; NDF; SMDF |
背景介绍 |
neuregulin-1 (heregulin-1,NRG1) is a member of neuregulin family, which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. NRG1 isoforms can be classified into type I, type II and type III isoforms. NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart. |
注意事项
本司产品仅用于科研,不用于临床诊断