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产品展厅
Recombinant Human IL-1RAcP (Q9NPH3-2, C-6His)
  • 品牌:EnkiLife
  • 产地:中国
  • 型号:50μg
  • 货号:PHH0892
  • 价格: ¥880/支
  • 发布日期: 2025-06-23
  • 更新日期: 2025-06-23
产品详请
产地 中国
品牌 EnkiLife
货号 PHH0892
用途
包装规格 50μg
纯度 95%
CAS编号
是否进口
产品名称

Recombinant Human IL-1RAcP (Q9NPH3-2, C-6His)

英文名称

IL-1RAcP/IL1R3/IL-1 Receptor Accessory Protein (Q9NPH3-2,Ser21-Gln356)  

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素

<1 EU/μg as determined by LAL test.

蛋白构建

Recombinant Human Interleukin-1 Receptor Accessory Protein is produced by our Mammalian expression system and the target gene encoding Ser21-Gln356 is expressed with a 6His tag at the C-terminus.

Accession

Q9NPH3-2

表达宿主

Human Cells

种属

Human

预测分子量

39.75 KDa

制剂

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

运输方式

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

稳定性&储存

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

复溶

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

分子别名
Interleukin-1 Receptor Accessory Protein; IL-1 Receptor Accessory Protein; IL-1RAcP; Interleukin-1 Receptor 3; IL-1R-3; IL-1R3; IL1RAP; C3orf13; IL1R3

 

背景介绍
Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1α, IL1βand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.

 

注意事项

本司产品仅用于科研,不用于临床诊断和治疗