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- 品牌:EnkiLife
- 产地:中国
- 型号:50μg
- 货号:PHH0892
- 价格: ¥880/支
- 发布日期: 2025-06-23
- 更新日期: 2025-06-23
产地 | 中国 |
品牌 | EnkiLife |
货号 | PHH0892 |
用途 | |
包装规格 | 50μg |
纯度 | 95% |
CAS编号 | |
是否进口 | 否 |
产品名称 |
Recombinant Human IL-1RAcP (Q9NPH3-2, C-6His) |
英文名称 |
IL-1RAcP/IL1R3/IL-1 Receptor Accessory Protein (Q9NPH3-2,Ser21-Gln356) |
纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
内毒素 |
<1 EU/μg as determined by LAL test. |
蛋白构建 |
Recombinant Human Interleukin-1 Receptor Accessory Protein is produced by our Mammalian expression system and the target gene encoding Ser21-Gln356 is expressed with a 6His tag at the C-terminus. |
Accession |
Q9NPH3-2 |
表达宿主 |
Human Cells |
种属 |
Human |
预测分子量 |
39.75 KDa |
制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
稳定性&储存 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
分子别名 |
Interleukin-1 Receptor Accessory Protein; IL-1 Receptor Accessory Protein; IL-1RAcP; Interleukin-1 Receptor 3; IL-1R-3; IL-1R3; IL1RAP; C3orf13; IL1R3 |
背景介绍 |
Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1α, IL1βand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor. |
注意事项
本司产品仅用于科研,不用于临床诊断和治疗