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- 品牌：EnkiLife
- 产地：中国
- 型号：50μg
- 货号：PHM0992
- 纯度：95
- 价格： ￥1100/支
- 发布日期： 2025-06-23
- 更新日期： 2025-06-23
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 货号 | PHM0992 |
| 用途 | |
| 包装规格 | 50μg |
| 纯度 | 95% |
| CAS编号 | |
| 是否进口 | 否 |
| 产品名称 | Recombinant Mouse IL-18BPd (C-Fc) |
| 英文名称 | IL-18 BPd/Interleukin-18 binding protein isoform d |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 | <1 EU/μg as determined by LAL test. |
| 蛋白构建 | Recombinant Mouse Interleukin-18 Binding Protein Isoform d is produced by our Mammalian expression system and the target gene encoding Thr29-Ala193 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession | Q9Z0M9 |
| 表达宿主 | Human Cells |
| 种属 | Mouse |
| 预测分子量 | 45.1 KDa |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Interleukin 18 Binding Protein Isoform d; IL-18 BPd;Interleukin-18-binding protein;Interferon gamma-inducing factor-binding protein;Igifbp |
| 背景介绍 |
| Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interaction between IL-18 and IL-18BP has a significant role in the inflammation process. IL-18 BPs have four isoforms, a, b, c and d, which are spliced by different ways. The IL-18 BP isoforms a and c each contain one immunoglobulin (Ig)-like C2-type domain which is essential to the binding and neutralizing properties of the binding proteins. The IL-18 BP isoforms b and d lack a complete Ig domain. The expression of IL-18 and the IL-18BP are indentified in immune tissues such as the spleen, but also in nonimmune cells including keratinocytes. |
注意事项
本司产品仅用于科研,不用于临床诊断