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- 品牌:EnkiLife
- 产地:中国
- 型号:50μg
- 货号:PEH1225
- 纯度:95
- 价格: ¥1100/支
- 发布日期: 2025-06-23
- 更新日期: 2025-06-23
产地 | 中国 |
品牌 | EnkiLife |
货号 | PEH1225 |
用途 | |
包装规格 | 50μg |
纯度 | 95% |
CAS编号 | |
是否进口 | 否 |
产品名称 | Recombinant Human Beta-NGF |
英文名称 | beta-NGF/β-Nerve Growth Factor/β-NGF (Ser122-Ala241) |
纯度 | Greater than 95% as determined by reducing SDS-PAGE |
内毒素 | <0.01 EU/μg as determined by LAL test. |
蛋白构建 | Recombinant Human Beta-Nerve Growth Factor is produced by our E.coli expression system and the target gene encoding Ser122-Ala241 is expressed. |
Accession | P01138 |
表达宿主 | E.coli |
种属 | Human |
预测分子量 | 13.4 KDa |
制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
运输方式 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
稳定性&储存 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
分子别名 |
Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB;β-NGF |
背景介绍 |
Human β-Nerve Growth Factor (β-NGF) was initially isolated in the mouse submandibular gland. It is composed of three non-covalently linked subunits α, β, and γ; it exhibits all the biological activities ascribed to NGF. It is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. Β-NGF is a neurotrophic factor that signals through its receptor β-NGF, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. These results suggest that β-NGF is a pleiotropic cytokine, which in addition to its neurotropic activities may have an important role in the regulation of the immune system. Human β-NGF shares 90% sequence similarity with mouse protein and shows cross-species reactivity. |
注意事项
本司产品仅用于科研,不用于临床诊断