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产品展厅
Recombinant Mouse SCF
  • 品牌:EnkiLife
  • 产地:中国
  • 型号:50μg
  • 货号:PEM1572
  • 纯度:95
  • 价格: ¥1780/支
  • 发布日期: 2025-06-23
  • 更新日期: 2025-06-23
产品详请
产地 中国
品牌 EnkiLife
货号 PEM1572
用途
包装规格 50μg
纯度 95%
CAS编号
是否进口
产品名称

Recombinant Mouse SCF

英文名称

SCF/Stem Cell Factor/c-kit Ligand/KITLG

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素

<0.01 EU/μg as determined by LAL test.

蛋白构建

Recombinant Mouse Stem Cell Factor is produced by our E.coli expression system and the target gene encoding Lys26-Ala189 is expressed.

Accession

P20826

表达宿主

E.coli

种属

Mouse

预测分子量

18.4 KDa

制剂

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

运输方式

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

稳定性&储存

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

复溶

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.


分子别名
Kit ligand; Hematopoietic growth factor KL; Mast cell growth factor; MGF; Steel factor; Stem cell factor; SCF


背景介绍
Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5.


注意事项

本司产品仅用于科研,不用于临床诊断