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产品展厅
Recombinant Human CCL26 (71AA)
  • 品牌:EnkiLife
  • 产地:中国
  • 型号:50μg
  • 货号:PEH0266
  • 纯度:95
  • 价格: ¥2520/支
  • 发布日期: 2025-06-23
  • 更新日期: 2025-06-23
产品详请
产地 中国
品牌 EnkiLife
货号 PEH0266
用途
包装规格 50μg
纯度 95%
CAS编号
是否进口
产品名称

Recombinant Human CCL26 (71AA)

英文名称

CCL26/Eotaxin-3 (24-94)

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素

<1 EU/μg as determined by LAL test.

蛋白构建

Recombinant Human C-C Motif Chemokine 26 is produced by our E.coli expression system and the target gene encoding Thr24-Leu94 is expressed.

Accession

Q9Y258

表达宿主

E.coli

种属

Human

预测分子量

8.53 KDa

制剂

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM EDTA, 20% Glycerol, pH 9.0.

运输方式

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

稳定性&储存

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

复溶

0


分子别名
C-C Motif Chemokine 26; CC Chemokine IMAC; Eotaxin-3; Macrophage Inflammatory Protein 4-Alpha; MIP-4-Alpha; Small-Inducible Cytokine A26; Thymic Stroma Chemokine-1; TSC-1; CCL26; SCYA26


背景介绍
Chemokine Ligand 26 protein (CCL26) is a novel small cytokine belonging to the CC chemokine family which is involved in immunoregulatory and inflammatory processes. CCL26 is constitutively expressed in thymus, but only transiently expressed in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for CCL26 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant CCL26 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, CCL26 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. CCL26 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.


注意事项

本司产品仅用于科研,不用于临床诊断