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产品展厅
Recombinant Mouse FGF-4
  • 品牌:EnkiLife
  • 产地:中国
  • 型号:50μg
  • 货号:PEM2172
  • 纯度:95
  • 价格: ¥1680/支
  • 发布日期: 2025-06-23
  • 更新日期: 2025-06-23
产品详请
产地 中国
品牌 EnkiLife
货号 PEM2172
用途
包装规格 50μg
纯度 95%
CAS编号
是否进口
产品名称

Recombinant Mouse FGF-4

英文名称

FGF-4/Fibroblast Growth Factor 4 (Ser67-Leu202)

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素

<0.01 EU/μg as determined by LAL test.

蛋白构建

Recombinant Mouse Fibroblast Growth Factor 4 is produced by our E.coli expression system and the target gene encoding Ser67/xadLeu202 is expressed.

Accession

P11403

表达宿主

E.coli

种属

Mouse

预测分子量

15.2 KDa

制剂

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

运输方式

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

稳定性&储存

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

复溶

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.


分子别名
Fibroblast growth factor 4; FGF-4; Heparin secretory-transforming protein 1; HST; HST-1; HSTF-1; Heparin-binding growth factor 4; HBGF-4; Transforming protein KS3; FGF4; HST; HSTF1; KS3


背景介绍
Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF4 shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2c, 3c and 4, is spatially and temporally regulated during embryonic development. FGF-4 is proposed to play a physiologically relevant role in human embryonic stem cell selfrenewal. It promotes stem cell proliferation, but may also aid differentiation depending on context and concentration, and is often included in embryonic stem cell media in vitro. FGF-4 is mitogenic for fibroblasts and endothelial cells in vitro and has autocrine transforming potential. It is a potent angiogenesis promoter in vivo and has been investigated as therapy for coronary artery disease.


注意事项

本司产品仅用于科研,不用于临床诊断