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- 品牌：EnkiLife
- 产地：中国
- 型号：50μg
- 货号：PHM1711
- 纯度：95
- 价格： ￥1280/支
- 发布日期： 2025-06-23
- 更新日期： 2025-06-23
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 货号 | PHM1711 |
| 用途 | |
| 包装规格 | 50μg |
| 纯度 | 95% |
| CAS编号 | |
| 是否进口 | 否 |
| 产品名称 | Recombinant Mouse TGFBR2 (C-Fc) |
| 英文名称 | TGFBR2/TGF-beta RII/TGF-beta receptor type-2/Transforming Growth Factor-β Receptor Type II (Ile24-Asp159) |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 | <1 EU/μg as determined by LAL test. |
| 蛋白构建 | Recombinant Mouse Transforming Growth Factor-beta Receptor Type II is produced by our Mammalian expression system and the target gene encoding Ile24-Asp159 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession | Q62312-2 |
| 表达宿主 | Human Cells |
| 种属 | Mouse |
| 预测分子量 | 42.3 KDa |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II; Tgfbr2 |
| 背景介绍 |
| Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinity cell surface receptors: TGF-β receptor type I (TGF-β-RI), TGF-β receptor type II (TGF-β-RII), and TGF-ββ receptor type III (TGF-β-RIII). TGF-β RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. |
注意事项
本司产品仅用于科研,不用于临床诊断