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- 品牌：EnkiLife
- 产地：中国
- 型号：50μg
- 货号：PEH1312
- 纯度：95
- 价格： ￥1780/支
- 发布日期： 2025-06-23
- 更新日期： 2025-06-23
| 产地 | 中国 |
| 品牌 | EnkiLife |
| 货号 | PEH1312 |
| 用途 | |
| 包装规格 | 50μg |
| 纯度 | 95% |
| CAS编号 | |
| 是否进口 | 否 |
| 产品名称 | Recombinant Human Persephin |
| 英文名称 | Persephin |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 | <1 EU/μg as determined by LAL test. |
| 蛋白构建 | Recombinant Human Persephin is produced by our E.coli expression system and the target gene encoding Ala61-Gly156 is expressed. |
| Accession | O60542 |
| 表达宿主 | E.coli |
| 种属 | Human |
| 预测分子量 | 10.4 KDa |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
| 运输方式 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 4mM HCl.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Persephin; PSP; PSPN |
| 背景介绍 |
| Persephin is a secreted protein, belongs to the glial cell linederived neurotrophic factor (GDNF) family of the TGF-β superfamily. It shares 38-46% amino acid (aa) identity with family members GDNF, neurturin and artemin. It is expressed at very low levels in most tissues. Mature protein contains a signal sequence, a pro-domain and a 96 aa mature sequence with several cysteines that are conserved among family members. It circulates as an unglycosylated disulfide-linked homodimer. Like other GDNF family members, Persephin acts through engagement of GRFα4, a glycosylphosphatidylinositol (GPI)-linked GDNF receptor family Persephin is reported to promote both the survival and growth of central dopaminergic and motor neurons, and kidney development. These effects are correlated with the expression patterns of GFRα4, and RET. |
注意事项
本司产品仅用于科研,不用于临床诊断